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Jesse sets out to use the Voice to solve the troubles of the people of Annville. Meanwhile, Odin agrees to a meeting with the Green Acres people, Donnie realizes what he's up against, and Tulip and Cassidy begin a relationship.
Cassidy tries to keep Fiore and DeBlanc off of Jesse after they express their willingness to cut open the preacher with a chainsaw. Meanwhile, Jesse approaches Odin with an offer: the church land if Odin doesn't accept God.
After DeBlanc and Fiore tell Jesse about the source of the Voice, they receive a visit from a higher angel. Meanwhile, Emily and Tulip bond, and Eugene asks Jesse to take back what he did.
When Texas preacher Jesse Custer is inhabited by the renegade spawn of an angel and a demon, he gains the power to control people with just a word. Now Jesse, his badass ex Tulip, and his friend Cassidy (who happens to be a vampire) are thrust into a twisted battle spanning Heaven, Hell and everywhere in between.