When the Leader hijacks Iron Man's Hulkbuster suits to destroy the Agents of S.M.A.S.H., the team and Iron Man must learn to trust each other and work together to defeat the Leader.

The Hulks face their biggest foe yet when they travel into space to battle Ego the Living Planet, who threatens to tear Earth apart! To survive, they have to tackle the second biggest ego in the galaxy -- Red Hulk's.