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Sister Julienne cares for a pregnant prostitute, while Dr Turner puzzles over a mysterious string of symptoms.
Dr Turner and Nurse Crane must deal with an alarming outbreak of diphtheria. Fred finds an abandoned baby in a dustbin, and the team must help locate its mother.
Lucille is trapped in a lift with a woman in labour while working at St Cuthbert's, and Nurse Crane helps a Sylheti woman with fistula.
As the unfamiliar terrain of the Hebrides stretches the team to the utmost at Christmas, their return to Poplar sees them braving a landscape that feels suddenly unfamiliar. Budgets are being cut, and hospitals reorganised. Terraced houses are being demolished, and traditional family structures torn apart. There are wrecking balls everywhere, and it's up to Sister Julienne, and the midwives and medics of Nonnatus House, to help find a way out of the rubble. When they themselves come under threat, their job becomes even harder.