Lupo and Bernard are called in to investigate the death of a young heiress, Annie Douglas (Morgan Lynch), who died of an apparent drug overdose. The detectives begin to suspect her cousin, Randy Colwyn (Daniel Abeles), whose inheritance was increased due to Annie's death. As the investigation continues, Annie's greedy relatives reveal another recent loss in the group. The case becomes more than a family matter as an experimental cancer clinic, fraudulent adoptions and unborn children are tied into the case.

When a television crew from a style show goes in search of a fashion victim, Marielle Di Napoli (Anna Gunn), they find a murder victim instead. As Detectives Lupo and Bernard investigate this unusual crime, they begin to suspect the victim's wife, who has a violent and peculiar past. The case is further complicated when detectives discover the truth behind the victim's financial situation: they learn that the victim may have backed out of a conspiracy with fellow husbands to hide assets from their wives until their divorces.