On suspension for interfering in an investigation and on the run for surreptitiously freeing a murderer to make amends, Detective William Murdoch leaves Toronto for the Klondike Gold Rush, intent on a life beyond policing. While there he stumbles upon a murder investigation and soon realizes his days as a detective are not behind him.

When Detective Murdoch investigates a series of deaths linked to an exhibition of Egyptian antiquities, Constable Crabtree is convinced a mummy's curse is to blame.