After Steve gets in a bad accident and is saved by Jesse, he has to spend a few days in the hospital to recover. However, still slightly under the effects of anesthesia, Steve witnesses what he believes to be a murder and tries to get Mark and the others to believe what he saw. He then begins to investigate and soon discovers that the murder involves a respected doctor who appears to have a few secrets he was trying to keep hidden.

One of Mark's med students, Alex, is a contestant on a Big Brother type reality show, hoping to win the grand prize so he can use it to pay off his student loans. When a fellow contestant ends up murdered, Mark takes the victim's spot on the show, with the hopes to find out the killer, he finds out the real reason why the contestant was targeted and how the killer almost got away with their crime.