In a Project Runway first, the designers are asked to design menswear for football great Tiki Barber. A gaggle of male models invade the workroom and flummox most every designer. But the challenge proves terribly difficult. Some designers have never sketched menswear, and most are having trouble with the patterns. As each look walks down the runway, some looks are exceptional, and some are not finished. In the end, Jack's classic dress shirt and pants win the challenge, but Carmen's time-constraints prove to be her downfall.

The designers are asked to re-style the outfits of 12 women, all of whom have lost a significant amount of weight. Standing on the runway in clothes that are much too big, the woman are paired off with a designer.   All is going well, until Jack reveals that he has developed a staph infection in his face, and must leave the competition. The shell-shocked designers are discombobulated further by news that previously-auf'd designer Chris March will return to the competition.   In the end, Christian's two-piece design wins the competition, while Steven goes home for "turning a wedding dress into a funeral dress."