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Iain questions those closest to him, Nicole decides to make a difference, whilst Flynn and Dylan clash over how to tackle a drug crisis.
The ED is overwhelmed by an influx of teens, while Siobhan worries about the nurses out at a nightclub. Nicole is compromised, and Faith grows suspicious of the paramedics.
Jacob is furious that he's Iain's number one suspect for the missing morphine, Cam's career is threatened after an accusation is made, and Ngozi worries that she might lose Nicole forever.
They're fighting to save patients while their personal lives are brimming with drama and intrigue. Everything's at stake on the emergency ward.