UFC Fight Night 78: The Ultimate Fighter Latin America 2 Finale is a Welterweight main event card between Neil Magny (16-4-1, 5 KO's) from Arvada, Colorado going against Kelvin "Mini Cain" Gastelum (11-1-0, 4 KO's) from Yuma, Arizona. This card is being broadcast live from Arena Monterrey in Monterrey, Mexico. The scheduled undercard bouts are as follows:

Featherweight: Ricardo Lamas vs. Diego Sanchez

Flyweight: Jussier Formiga vs. Henry Cejudo

Welterweight: Erick Montaño vs. Enrique Marín

Lightweight: Enrique Barzola vs. Horacio Gutiérrez

Lightweight: Efrain Escudero vs. Leandro Silva