UFC Fight Night 100: Bader vs. Nogueira 2 is a mixed martial arts Light Heavyweight main event produced by the Ultimate Fighting Championship between Ryan "Darth" Bader (21-5-0, 7 KO's) from Reno, Nevada going up against Antônio Rogério "Little Nog" Nogueir (22-7-0, 7 KO's) from Gardena, California. This card is airing live tonight from the Ginásio do Ibirapuera in São Paulo, Brazil. This is the Preliminary card of bouts.

The scheduled Preliminary bouts are as follows:

Bantamweight: Johnny Eduardo vs. Manvel Gamburyan

Heavyweight: Luis Henrique vs. Christian Colombo

Light Heavyweight: Marcos Rogério de Lima vs. Gadzhimurad Antigulov

Middleweight: Cezar Ferreira vs. Jack Hermansson