Dr. Halstead and Sharon Goodwin deal with a husband intent on harvesting his recently deceased wife's eggs, but soon discover some vital information that surprises everyone. Dr. Charles is brought in by Dr. Choi to aid a patient who is trying to remove his own arm from his body because he feels like it doesn't belong. Nurse Sexton befriends the father of a child who is rushed into the hospital after swallowing magnets - a situation that Dr. Rhodes and Dr. Manning are concerned could present dangerous complications. Meanwhile, Sarah Reese finally learns about where she will do her residency, but has last-minute second thoughts

Dr. Manning and Dr. Charles deal with a 16-year-old patient suffering from abdominal pain who adamantly refuses any drugs for fear of winding up like her drug-addicted father. Dr. Halstead relives a bit of his past when a patient, along with his brother, turn out to be former high school classmates whose past history with him is anything but stellar. Meanwhile, Dr. Choi works on a woman 32 weeks pregnant who has a big reason to do everything in her power not to deliver the child, much to the dismay of Goodwin, Charles and the hospital staff. Elsewhere, April is less than thrilled to discover her brother Noah has an enterprising side-business that involves her new boyfriend Tate Dr. Rhodes avoids meeting up with his sister Claire so he doesn't have to deal with family issues.