The effects of the supply chain shortages continue to impact the E.D. when Vanessa's drug dealer reappears. One of the victims of the recent train crash needs a transplant, forcing Crockett to improvise. Charles and Nellie help a patient with amnesia.

Med runs out of scrubs, forcing the staff to improvise. The life of Archer's son is in danger. Crockett and Charles help a kidney transplant patient experiencing psychosis. Hannah and Will grow closer.