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An infection threatens Crockett's risky liver transplant. Maggie and Charles help a struggling burn unit nurse. Goodwin is forced to make a tough decision about Bert's future.
Ripley struggles to keep Sully's diagnosis a secret when the latter's pregnant girlfriend comes to Med for help. Loren works to earn a spot in Med's trauma fellowship. Charles and a medical student treat a bipolar artist.
Ripley and Charles treat a high-risk prisoner who may have dementia. Archer and Sean clash when a resident from Margo's facility lands in the E.D. Crockett receives shocking news.