This trip, Guy's hittin' up some joints that'll warm the palate and the soul. In Portland, Ore., the funky neighborhood cafe cranking out comfort foods like the heartless artichoke sandwich and a curried lentil dish that hits all the right notes. In Albuquerque, N.M., a double duty brewery is serving up soul food with a New Mexico twist, like southern fried chicken and crackling cornbread. And in Kansas City, Mo., the barbecue and blues joint with a die-hard barbecue competitor dishing up regional favorites like burnt ends and battered fries and a local NASCAR hero to boot.

This trip, Guy's headed south of the border to Cabo San Lucas, Mexico. On the town's main drag, the taco joint that's turning out totally fresh octopus tacos and Guadalajaran-inspired sauces that'll knock your socks off. On the marina, the all day spot dishin' up stuffed fish with lobster sauce and a unique spin on French toast. And down the dock, another marina favorite serving up a taquito trifecta alongside super fresh sushi with Mexican flair.