On DDD, Guy's seen a ton of sammies and there are a few he'll not soon forget. From the traditional, like the po-boys he whipped up with Emeril Lagasse at Mahoney's Po-Boy Shop, to the ethnic, like the outrageous arepas at Pica Pica, to the downright ducky French dip at Beer Belly. The meat in the middle's taking center stage in standouts like the Smack Shack where the lobster is bursting from the bun and at The Refuge where Guy's divin' into an all-out pastrami extravaganza. These joints are bringin' the old bagged lunch staple to a whole new level.

This trip, Guy's gettin' into the heart of some long-standing traditions. In Miami, Fla., the Asian fusion spot delivering the bomb dot com Brussels sprouts and going all out ducky on the sous vide sammie. In Eureka, Calif., the soul food spot takin' a page out of grandma's cookbook with down home favorites like jerk fried chicken and shrimp and crawfish etouffee. And in midtown New York, the Italian pizza maker schooling Guy and Iron Chef Geoffrey Zakarian on the authentic Neapolitan technique behind standout pizzas like pistacchio e salsiccia and montanara starita.