Guy Fieri's having a sandwich extravaganza! First, a lunch spot in Indianapolis is serving up serious flavors with the-bomb brisket au jus and rockin' roast pork. Then in San Luis Obispo, Calif., a next-level burger joint is plating killer barbacoa and a legit tri-tip dip. Plus, a San Antonio brewpub is scratch making a sourdough Rueben and puttin' out pastrami pizza with a punch.

This trip, Guy Fieri's gettin' into mega Mexican, mac 'n' cheese and prime-time pie. There's lights-out Latin in Chicago putting an upscale spin on shrimp empanadas, the-bomb birria grilled cheese, and a handcrafted hibiscus-tequila pairing. In Tallahassee, Fla., a macaroni mixologist is going out of bounds with grandma's recipes, adding mouthwatering mojo pork and cookin' up masala mac bites. And a GGG alum in Minneapolis is firin' up from-scratch flavor bombs at his pizza trailer, topping things off with truffle shrooms, shishito and sausage.