If Hurricane Milton stays on its current track, forecasters say it will be the worst storm to hit the Tampa, Florida, area in more than a century. Lonnie Quinn has new details on Milton's track and timing. Hurricane Milton exploded in strength Monday with winds topping 180 miles per hour. The monster hurricane is now expected to make landfall late Wednesday or early Thursday in Florida. Cristian Benavides and Tom Hanson report. One year ago, Hamas fighters launched a brutal terrorist attack on Israel, killing more than 1,200 people and kidnapping 250 more. About 100 are still in captivity, including seven Israeli Americans. Elizabeth Palmer reports from Tel Aviv on the horrors of the attack and the unresolved conflict.Former President Donald Trump marked Oct. 7 at a memorial in Queens, New York, while in Washington, Vice President Kamala Harris planted a pomegranate tree, a symbol of a hope. Nancy Cordes has more on how Israel's war with Hamas is unavoidably a factor in the U.S. presidential election. As Florida braces for Hurricane Milton, North Carolina is still grappling with the crushing destruction of Helene and its ripple effects. Tonight, the key battleground state is changing some of its voting rules to make it easier for people to cast their ballots. Skyler Henry reports. Two scientists' groundbreaking research on worms has earned them the Nobel Prize in medicine. Victor Ambros and Gary Ruvkun uncovered microRNA, tiny molecules that help control what cells do, which could help develop new medicines. 

Hurricane Milton is projected to make landfall over Florida's west coast in the early morning hours as a major hurricane. Rob Marciano has the latest on the storm's projected path. Some Tampa residents have not heeded evacuation warnings ahead of Hurricane Milton's arrival. As of Wednesday evening, the National Weather Service said those who hadn't left yet shouldn't try to evacuate and instead shelter in place. Jonathan Vigliotti speaks with some of the residents who chose to stay. Florida Gov. Ron DeSantis said Wednesday evening that Florida is "absolutely" prepared for the arrival of Hurricane Milton, which is forecast to be one of the strongest to hit the region in decades. He also said "people heeded the call" to evacuate areas which are expected to be hard-hit. DeSantis spoke to "CBS Evening News" anchor and managing editor Norah O'Donnell. Fort Myers, Florida, which was devastated by Hurricane Ian two years ago, is expected to see a massive storm surge from Milton. Ahead of the hurricane's arrival, several tornadoes are suspected to have hit the area. Nicole Valdes has more. As Milton approaches Florida's west coast, several airports and iconic theme parks have already closed down. Manuel Bojorquez gives an update on the preparations for the hurricane's arrival. While Milton will make landfall over Florida's west coast, the storm is expected to continue moving east and maintain hurricane strength the entire time it's over Florida's peninsula. Tom Hanson reports on how the state's east coast is preparing for the storm.