In a dramatic docudrama, NOVA reconstructs the controversial lawsuit raised against renowned heart surgeon Dr. Denton Cooley when one of his patients died after heart surgery, and examines the legal and moral issues this raises in the practice of modern medicine.

NOVA investigates the theories of von Daniken and others that the Earth has been visited by intelligent beings from outer space. Among claims examined are: that the building techniques used in the Great Pyramid of Cheops are so advanced that only an extraterrestrial intelligence could have built it; and that the engraved stones of Palenque in Mexico depict an ancient astronaut at the controls of a space rocket.