Still grieving for Arthur, Ric questions his surgical skill when he faces losing another young man. Oliver realises he needs to mend his own heart and move on from his relationship with Zosia when he treats a patient with a malfunctioning mechanical heart. When Jason observes the ward, Serena finds herself not only clashing with Bernie but also under scrutiny from her nephew.

Guy must face his past when an unexpected patient arrives at Holby. Fletch struggles with single parenthood as his home and work lives collide. Ric makes a new enemy in his bid to become deputy CEO.