It is crunch time for Mo, who has some difficult life choices to make - will she ultimately be led by her head, or will she follow her heart? A patient who is dear to Ric forces him to try to mend some broken ties, but is it too little too late? Jasmine has growing suspicions of Fran's intentions with Jac - could she be on to something?

Wrestling with her feelings in the wake of tragedy, Jac buries herself in work, determined to save the life of a scared and fatalistic patient. Donna Jackson returns to Holby on its darkest of days, but can she find her place in a hospital that has changed so much? Sacha is forced to confront his faith when his religious mother sets him up on a blind date.