Nina receives surprising news that throws her entire future with estranged husband Matteo into question. While trying to rally morale on a despondent Keller, Nina offers the registrars an opportunity that only increases the brewing rivalry between Fredrik and Dom. When Fredrik inadvertently learns her secret, Nina must decide if she can trust him.

Oliver's high hopes to resurrect his research project are dashed when a face from the past arrives as the new consultant neurosurgeon, carrying with her a research proposal of her own. When his patient requires a neuro consultation, Oliver is forced to work with his rival, unearthing painful memories of his late wife Tara.

After transferring to AAU, Lofty struggles to find his place on the busier ward. His meticulous approach to treating a notorious patient clashes with a recently promoted and overstretched Morven. Can Lofty convince Morven to slow down and remember why she became a doctor in the first place?

Hanssen faces a fight for Holby's survival as the prospect of a merger hangs over them. He finds strength in an unexpected source, as Sacha rallies to his side and brings the fight to Keller. Will they be successful?

It is Donna's first day back since the coroner's court, and she feels everyone judging her. Her problems are compounded by having to deal with an unwanted visitor.

Oliver is trying to settle into his new single life. When he obsesses over a lost possession, a frustrated Matteo encourages him to find a way to move on from Zosia.