Mike Barratt arrives back in Holby City to run Keller Ward, a new general surgery ward. His team are thrown in at the deep end when they are forced to choose between saving the guilty or the innocent after a racist attack.

When Anton Meyer's sister arrives needing a heart operation, he stands to inherit her money if things go awry, while facing the disapproval of her husband. Jasmine Hopkins is inundated with work on her first day as nurse practitioner.