A psychiatrist visits ERs, jails and homeless camps to tell poignant stories behind mental illness.

The story of one warmhearted, stubborn man's visionary quest to find a cure for cancer, Jim Allison: Breakthrough is an homage to an unconventional superhero — a pioneering, harmonica-playing scientist from a small town in Texas who triumphed over a doubtful medical establishment to save innumerable lives around the world and win the Nobel Prize.