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Isabel and Fernando return to dressing in mourning. His eldest daughter, his heiress, his hope dies in the birth of Miguel de la Paz.
After the premature death of Prince Juan, the kings rush to swear as heirs to Isabel and Manuel, although they expect problems with the Cortes de Aragón. The Archduke Philip, who already lurks the throne of Castile and Aragon, begins to profile itself as an enemy instead of the ally they sought and seeks the support of the King of France to make his claims true.
Years after its conquest, Granada remains mostly Muslim. Isabel and Fernando send Cisneros to speed up the conversions. This, against the criterion of Talavera, imposes Christianization by the good and the bad.
Miguel de la Paz dies and the queen falls down. Misfortune does not leave the court ... Felipe is the new Prince of Asturias