Documentary following animal rights lawyer Steven Wise in his unprecedented challenge to break down the legal wall that separates animals from humans. Steve and his legal team are making history by filing the first lawsuits that seek to transform an animal from a thing with no rights to a person with legal protections. It is an intimate look at a lawsuit that could forever transform our legal system, and one man's lifelong quest to protect 'nonhuman' animals. Supported by affidavits from primatologists around the world, Steve maintains that, based on scientific evidence, cognitively complex animals such as chimpanzees, whales, dolphins and elephants have the capacity for limited personhood rights. Filing lawsuits used to free humans from unlawful imprisonment, Wise argues on behalf of four captive chimpanzees in New York State. The film captures a monumental shift in our culture, as the public and judicial system show increasing receptiveness to Steve's impassioned arguments.

Paolo Macchiarini is one of world's most famous surgeons. He hopes to revolutionize medicine by creating a new type of synthetic organ - a vision that could save many lives. But the Italian surgeon has also been accused of using terminally ill patients as human guinea pigs as well as falsifying his science. Is he a genius - or is he behind one of medicine's biggest scandals?

This gripping investigative series gains access to Macchiarini's closed world of organ transplants, animal experiments and stem-cell research. From his base at one of the world's most prestigious medical institutions - the Karolinska Institute, home of the Nobel Prize in Stockholm, Sweden - the series explores the fallout from his work across the world, from London to Russia. It poses a fundamental ethical question - how far can you risk a human life in the name of cutting-edge science?