Yamato Kazakiri, a zoologist, uncovers Zyuland, a world inhabited by an anthropomorphic animal race known as the Zyumans (ジューマン, Jūman). However, it coincides with the arrival of the Dethgaliens (デスガリアン, Desugarian) from outer space who have chosen Earth to be the site of their 100th Blood Game (ブラッドゲーム, Buraddo Gēmu) competition. Four of the Zyumans – the shark woman Sela, the lion man Leo, the elephant man Tusk, and the white tiger woman Amu – try to defend Zyuland from the Dethgaliens but their fight takes them to Earth, with Yamato in tow, and it is revealed that he possesses an artifact known as the Champion's Proof, the fifth of a set also possessed by his Zyuman companions. The Champion's Proofs transform into devices that allow the five of them to transform into the Zyuohgers and fight the Dethgalien general attacking the Earth.