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Missionairy Abigail Newkirk finds a replacement driver, Sam Livingston, who is traveling with his friend Cass Fleming.
Charlie takes a baby--and the only survivor of a stagecoach stricken by bubonic plague--thinking that the townspeople mean to kill it
A medicine man, Shadrack Bennington, abandons his partner and joins the train. Shadrack soon charms a woman and an orphan, but then abandons them when the train reaches San Francisco.