Bull confronts his guilt over closing his psychiatric practice to start TAC when his former patient, a young woman who is a clinical sociopath, goes on trial for killing her brother. When Bull and Benny's client has no memory of the crime due to her mental condition, they enter a "Not Guilty by Reason of Insanity" plea and aim to seat jurors that are sympathetic to mental illness.

Gabriel is arrested for being in the country illegally and threatened with deportation. Also, Bull represents a German national who is being sued by a museum over possession of a valuable painting.