Bull assists in the murder trial defense of an old friend, Vivian Cahill, an in-debt professional gambler accused of killing her wealthy father to gain her inheritance. Knowing their client had a complicated relationship with her father, Bull and Benny enter into voir dire looking for jurors who sympathize with dysfunctional family relationships

Bull takes on the trial defense of Dr. Natalie Reznick, an expert on anthrax, who is accused of orchestrating a series of anthrax attacks that terrorize the city. While the facts are against her, Bull sets out to prove the city was in such a rush to get the bacteria off the streets and calm the public's hysteria, they arrested the wrong person.