Bull takes on the trial defense of Dr. Natalie Reznick, an expert on anthrax, who is accused of orchestrating a series of anthrax attacks that terrorize the city. While the facts are against her, Bull sets out to prove the city was in such a rush to get the bacteria off the streets and calm the public's hysteria, they arrested the wrong person.

Bull mounts the defense of an idealistic state judge, Judge Duggan, who's on trial for obstruction of justice after she helped a trial witness evade federal arrest in her courtroom. During voir dire, Benny looks for jurors who believe the law is open to interpretation and that Judge Duggan broke the law to uphold courtrooms as sacred spaces within the justice system.