Joining guest host Virginia Trioli in Melbourne are Panellists: Matt Canavan, LNP Senator for Queensland; Lisa Singh, Tasmanian Labor Senator; Peter Singer, Renowned philosopher and ethicist; Celeste Liddle, Indigenous writer and commentator; and Kate Roffey, Former CEO of the Committee for Melbourne.

Panellists: Greg Hunt, Minister for Industry, Innovation & Science; Linda Burney, Shadow Minister for Human Services; Brian Cox, Particle Physicist and TV Presenter; Lily Serna, Mathematician and TV Presenter; and Malcolm Roberts, One Nation Senator-elect for Qld.