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Vanessa and Susan are chased by mutated feral vampires in the sewers, arriving back at the hospital only after a hostile takeover.
Vanessa, now in the clutches of Julius and his vampire brood, is forced to demonstrate her powers; the refugees discover a serial killer among the residents, and plot to wrestle control from Axel.
Vanessa and Axel lead the hospital's last stand against a siege by Julius and his vampire soldiers; Dmitri's arrival with his vampire "Death Squad" reveals a possible civil war brewing among the two vampire factions.