It is 2019, most of humanity has turned into vampires. Axel MIller guards a facility where a mysterious woman called Vanessa is in some kind of coma. She awakes when vampires are attacking the facility, she seems to be special and may hold the key to save the world.

When the hospital's power source is damaged, Vanessa and the survivors only have three hours of reserve power for the UV lights - the only thing keeping the vampires at bay. While Vanessa and Axel head into the ruins of Seattle to scavenge parts, the others are left to fight: against both vampires and amongst themselves.