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Ian is faced with performing a surgery on a Jane Doe NICU patient while he continues to struggle with his personal issues. Meanwhile, Conrad asks Devon to cover his shift so he can spend a day at home with an anxious Gigi.
When a gunshot victim comes into the ER, his injuries prove to be so catastrophic throughout his body that multiple doctors need to jump on the case. Meanwhile, Ian is faced with a mandatory drug test and Padma prepares for her C-section.
A college professor comes into the ER and Conrad realizes it's a former patient of his from when he was an intern. Meanwhile, Devon ends up admitting a man - who swears by an anti-aging regimen that he thinks is the answer to eternal life - into the hospital after he collapses.