The doctors are facing a challenge when a pregnant patient is admitted with an aggressive brain tumor. Meanwhile, Claire has to face some cold hard truths about how patients of color are treated compared to white patients when it comes to being prescribed pain killers and other medications. Shaun turns to Lea for advice on how to deal with the feelings he has for a Radiology resident at the hospital. 

After bringing in an incredibly unique and complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room. Meanwhile, Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.