The team treats a famous marriage counselor after she injures her ankle from falling, but when she offers relationship advice to them, Dr. Morgan Reznick quickly spots that their patient might be experiencing something far more serious. Meanwhile, Dr. Audrey Lim is determined to get to the bottom of what really happened in the OR during her surgery and sets off on her own internal investigation.

Shaun, Asher and Powell treat a young patient on Halloween who has a rare hereditary disease, sending them down an uncharted path; Glassman and Shaun must overcome their differences to work together to try and find a solution for Lim's paralysis.