A woman hires Kimble to drive her daughter and herself to California. The young girl has a rabbit with her that had been a test subject in a research study and is infected with meningitis.

Kimble's joined on the run by Lt. Gerard's wife, who's had it with being no. 2 to a phantom. Kimble stumbles, signing his own name on a time-sheet, which sets off a manhunt, while residents battle a flood. Gerard drags his wife off of their vacation to join the hounds. With many roads out of the Midwest city under water, Marie Gerard and Kimble end up on the same Eastbound bus.