While working as a bartender, Dr. Kimble sees the one-armed man in a live news broadcast. After arriving on the scene Kimble chases the man which causes a woman to be hit by a car. While treating her at a hospital, he discovers she has had a relationship with the one-armed man and might be able to tell Kimble where he is.

As a posse of sheriff deputies pursue Dr. Kimble on foot in the desert, he is rescued by outlaw bikers who want to use him to settle a score with local law enforcement.