High school volleyball player Jeanna Giese complains she's fatigued and has numbness in her arm; then, she starts experiencing double-vision and loss of balance, making it clear she is suffering from something far more sinister than a sports injury.

Dr. Bill Lidner collapses just hours after returning home from a family trip overseas. His young daughters find him bleeding on the stairs of their Ohio home. They didn't know it then, but it is the first sign that something is very wrong.