Dr. Bill Lidner collapses just hours after returning home from a family trip overseas. His young daughters find him bleeding on the stairs of their Ohio home. They didn't know it then, but it is the first sign that something is very wrong.

Florida college student Lindsey Meyer and Michigan E.M.T Kevin Nesbit both come down with a painful sore throat. What seems like a symptom of the common cold, soon spirals into a life or death situation.