Following a failed assassination attempt on a U.S. senator, OA and Maggie are tasked with escorting her back to Washington, D.C. on a flight that becomes more perilous than imagined.

When a robbery at a community clinic turns deadly, the team investigates a drug trafficking crew and soon uncovers that the clinic's doctor may be more involved than they initially thought. Meanwhile, Isobel and her stepdaughter are at odds over a family issue.