Helen takes the reins at NHS Hampstead Hospital while Max gets creative to help a patient in need. Reynolds reaches a decision about Dr. Malvo. Iggy and Bloom help their patients understand the underlying cause of their stress. Dr. Wilder employs more unconventional techniques. 

As the team gathers to mourn the loss of someone dear, Max and Helen realize the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision while Reynolds decides to take his concerns for his patients to a new level. Dr. Fuentes once again reminds the New Amsterdam team who is in control.