The New Amsterdam team goes out for a night of karaoke and drinking, but must face the consequences at work the next day. Iggy helps a mysterious patient confront a past trauma. Reynolds and Dr. Malvo discuss their future. Leyla gives Bloom some bad news.

Max orchestrates a plan to get Dr. Fuentes terminated from New Amsterdam once and for all. Helen confronts her medical complication. Iggy helps two patients deal with a breakup, which forces him to consider his own marriage. Bloom and Dr. Castries reach an understanding.