A humiliated and jealous Evelyn exacts revenge by spreading the sordid secrets of Karen's past around Skelthwaite and patients soon refuse to be treated by her, leaving it up to Anna to discover why a teenage epileptic continues to suffer attacks despite his medication. Simon struggles to cope with the preparations for his forthcoming wedding and proves easy prey for Evelyn, who seems intent on wreaking as much havoc as she can.

The Skelthwaite Scorpions play a crunch match against rival team the Bridlington Trawlers, but fare badly, prompting David to demand a return engagement. Meanwhile, Anna's distress at her split with Simon is compounded by the financial hardship of running a business single-handed - but just as disaster looms, a shady businessman makes her an offer for the factory.