For the fourth time, Anderson Cooper and Andy Cohen co-host CNN's New Year's Eve Live celebration from Times Square in New York City to ring in 2021. Unlike prior years with large crowds of revelers, this year's event will be closed to the public due to the COVID-19 pandemic. But, first responders and medical personnel will be honored guests.

CNN performances and appearances will include John Mayer, Snoop Dogg, Patti Labelle, Jimmy Buffett, Carole Baskin, Josh Groban, Leslie Jordan, Dulce Sloan, Desus & Mero, Kylie Minogue, Aloe Blacc, Goo Goo Dolls, and Jon Bon Jovi. The program will also feature CNN's Ana Cabrera, Stephanie Elam, Randi Kaye, Richard Quest, Gary Tuchman, and Bill Weir from locations around the world.