Police in Idaho Falls, Idaho, have spent the last 23 years trying to solve the case of 18-year-old Angie Dodge who was raped and murdered in her own apartment in 1996. They turn to investigative genetic genealogist CeCe Moore, but no genetic genealogist has ever solved a case using such degraded DNA. Despite the challenge, Moore is able to come up with the name of the potential killer. The episode follows the Idaho Police Department as they track the suspect, collect his DNA and match it to the DNA found at the crime scene. Cameras are rolling as police move in for a heart-pounding arrest. Moore's work on this case also helps exonerate Chris Tapp, who was wrongly accused of Dodge's murder and spent 20 years in prison. The episode features interviews with Angie's mother, Carol Dodge; Idaho Falls Police Department's Captain Bill Squires; Detective Jeff Pratt; and reporter Bryan Clark. 

From 2006 to 2008, a series of unsolved rapes haunted residents in Fayetteville, North Carolina. Investigative genetic genealogist CeCe Moore works on the case with the Fayetteville Police Department while she attends CrimeCon, an annual true crime convention held in New Orleans. The episode includes interviews with survivor Kobi Haschen who bravely came forward with her story, Fayetteville Police Department's Lieutenant John Somerindyke and former supervisor Lieutenant Kellie Berg, sexual assault nurse examiner Liz Herring and reporter Paul Woolverton.