The killer of 8-year-old April Tinsley taunted police for decades in Fort Wayne, Indiana, leaving notes and threats with viable DNA samples, but they still couldn't catch him until now. Interviews featured in the episode include April's mother, Janet Tinsley, and cousin Kristina Snyder; Fort Wayne Police Department's Detective Brian Martin and retired detective Danny Jackson; coroner Chris Meihls; retired forensic scientist Linda McDonald; reporter Jamie Duffy; and Parabon NanoLabs' founder Steve Armentrout and director of bioinformatics Ellen Greytak. 

CeCe Moore gets an email from a St. George, Utah, detective asking her to work her first "hot" case, the rape of a 79-year-old woman that happened just three weeks prior. CeCe gets to work, knowing the rapist could easily strike again. Also: CeCe sees the first jury trial conviction from a case on which she worked, the suspect identified in the murder of Jay Cook and Tanya Van Cuylenborg from the series premiere.