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When Otto Octavius is caught in an explosion that fuses his robot arms to his body, Spider-Man sees the opportunity to recruit "The Octopus" into becoming a hero.
Spider-Man is targeted by a new costumed figure named Screwball for a series of online prank videos which block him from fighting crime.
Spidey invites The Octopus to patrol the streets alongside Miles and himself until it becomes clear that Otto isn't exactly a team player.