Spider-Man must find a way to stop Hobgoblin, who seems completely bent on doing whatever it takes to destroy Spider-Man.

Spider-Man takes on Doc Ock and his Sinister Five before they brainwash Spidey and destroy New York City.

It takes a last ditch, desperate effort for Spider-Man, Kid Arachnid, Anya and Harry to save Manhattan from the spider-monsters that the Jackal has created.

Peter and Harry must battle through an island of spider monsters to get to Norman Osborn, who appears to control them all; the boys discover the real mastermind.

Peter must find a way to cure Gwen Stacy and Norman Osborn after they turn into spider monsters; things get harder when Kraven the Hunter turns New York into his hunting grounds.

Everyone in Manhattan manifests spider powers; Spider-Man and Spider-Gwen must help Black Widow track down Crossbones before he delivers the vibranium to Arnim Zola and Hydra.

Spider-Man and Miles Morales track down an unidentified villain with spider-powers who steals Peter's experimental stealth suit and equipment from Horizon High and Oscorp Academy. 

Spider-Man must team up with Gwen Stacy and a reluctant Harry Osborn to investigate the truth behind the missing Raymond Warren aka the Jackal.

Peter spends a day at Oz Academy in the hopes of finding a clue that will convince Harry that his Dad is out to destroy Spider-Man.

Spidey invites The Octopus to patrol the streets alongside Miles and himself until it becomes clear that Otto isn't exactly a team player.

When Otto Octavius is caught in an explosion that fuses his robot arms to his body, Spider-Man sees the opportunity to recruit "The Octopus" into becoming a hero.

Spider-Man is targeted by a new costumed figure named Screwball for a series of online prank videos which block him from fighting crime.

The symbiote has escaped the Avengers Compound and attached itself to a new host. Now Spidey must find out how to beat it and who the new person is underneath.

Spidey must stop a low-level villain who has acquired some impressive freezing technology.

On Halloween night, Spider-Man must team up with the incredible Hulk to stop Man-Wolf, a super-strong gamma-powered werewolf, from infecting the rest of Manhattan.

Kraven the Hunter does a live broadcast of his hunt for Spider-Man.

When Miles Morales is bitten by an experimental spider and gains spider powers, Spider-Man must teach him the responsibilities of being a superhero.

After the terror of the symbiote, Spidey is off to the Stark Expo in his old costume. When Ghost hijacks the event, Spidey's only chance to save lives is to unleash the symbiote.

When Spider-Man uses his new black costume, he discovers that there is great danger in his new power; and he must find a way to defeat a costume that wants to destroy him.

Spider-Man meets the powerful, yet uncontrollable Sandman and helps him reunite with his estranged daughter with the help of the Venom symbiote.

Horizon High throws a dance in honor of Harry being exonerated, but Norman asked Harry to stay at Osborn academy.

As the new academy gets up and running, Norman holds auditions for enrollment, which deepens the rivalry between Oz Academy and Horizon High.

Norman Osborn creates the Osborn Academy for Geniuses as a way of saving his son Harry the embarrassment of being suspended from Horizon High.

Spider-Man must work to stop the Scorpion from wreaking havoc at the museum.

Peter is accepted into Horizon High, a school for geniuses, where his best friend Harry Osborn was just suspended; Peter makes his debut as Spider-Man and must battle the Vulture.