The impossible mission this time is to recover the multi-million dollar booty stolen by a family of smugglers. But when the action gets hot, Jim sustains a head injury and wakes up with amnesia and nothing but a fake ID to tell him who he is.

The IMF is sent to gather sufficient evidence on a former hoodlum to force him to testify against mobsters.

Gangsters running a loan-shark racket in Hawaii short-circuit the IMF team's investigation when they capture Willy and feed him gigantic doses of truth serum.

Posing as a "bag woman" for a crooked politician, Casey unknowingly carries an attached case locked to her wrist filled with both money and a bomb set to explode upon opening.

Nora Dawson, a witness to a murder, is committed to an asylum and is being systematically driven out of her mind with drugs when the IMF team is given twenty-four hours to save her life.

Barney assumes the identity of a powerful psychic from a Caribbean island kingdom in order to hypnotize a defecting crime syndicate leader into revealing his super secret list of government officials on the take.

An imprisoned private detective knows the location of a film roll that incriminates a mobster in murder.

Casey poses as a young peasant girl from Europe imported to be the bride of Joe Corvin, the top man at getting underworld millions into Swiss banks.

Jim Phelps and his IMF team are given the assignment of breaking an underworld ring attempting to set up one of the world's largest drug manufacturing plants off the coast of Africa.

Two gangsters attempt to gain control of all the illegal betting parlors in the country as well as a virtual takeover of all thoroughbred horse racing.

A psychotic ex-convict plans to get revenge on society with nerve gas.

The team stages an alien visit to influence a communications magnate who has sold a majority of his empire to the underworld.

Barney poses as a prospective rock-music recording artist to get evidence linking an organized crime figurehead to the sudden death of a beautiful recording star who was being blackmailed by the syndicate.

The IMF must retrieve material on America's nuclear arsenal, which a defense expert sold to a foreign power.

Stolen gems worth seventy-five million dollars are scheduled to be fenced to an underworld figure. After they suddenly disappear and the ship on which they were being transported is blown up at sea, the IMF team is assigned to the case.

Casey becomes an assassin's target when she attempts to get information from a mobster's alcoholic wife on his involvement in an intimidation racket and the cold-blooded murder of an employee.

An undercover agent is murdered while trying to intercept a huge heroin shipment in the Pacific Northwest, and the IMF team is called to take over and put the dealer and his chief executioner out of business.

The IMF sets out to stop two crime bosses extorting huge sums from every ship docking at a west coast port.

 To help the IMF team break up a crime syndicate that specializes in brainwashing ex-convicts into committing political assassinations, Barney substitutes for a former prisoner looking for an operation to give himself a new appearance. 

The leaders of two underworld factions call a top-level meeting at a ski resort to set up a financial holding company capable of creating chaos within the national economy.

The team must convince an aging mobster he is back in the 1930s to get evidence to close an unsolved case.

An FBI man is blinded while investigating a crime syndicate attempting to take over a large chemical plant. Jim Phelps undergoes a delicate eye operation so as to appear convincingly blind when he poses as the sightless man.